About Diagnoxal

The Technology

Diagnoxal runs a fixed sequence of diagnostic checks on every case. Every criterion is validated against the vignette before a diagnosis is suggested, and no conclusion is finalized while a medical or substance cause remains unexamined.

The Reasoning Pipeline

Each stage mirrors a check a careful clinician already runs; the value is that none of them is ever skipped.

• 1. Redact & Extract: In blinded mode, prior diagnostic labels are stripped first, the way a fresh consult starts. Symptoms, timeline, severity, exposures, and functional impairment are extracted from your free-text vignette.
• 2. Retrieve Criteria: DSM-5-TR and ICD-11 criteria are pulled for every candidate under consideration before any matching begins.
• 3. Hypothesize: Multiple diagnostic possibilities are raised at once, including medical mimics and substance or medication effects, so rare presentations are not overlooked.
• 4. Match Evidence: Every criterion is tested against quoted evidence from your vignette; criteria without support are marked unmet rather than assumed.
• 5. Differential: Each alternative is ruled in or out, with the supporting and opposing findings stated for the record.
• 6. Verify: The leading diagnosis is deliberately challenged, the way a colleague pushes back at case conference; weak matches are demoted.
• 7. Etiology Gate: While a medical or substance cause remains live (an unordered TSH, a new medication, escalating alcohol use), no primary psychiatric label is finalized. The formulation stays provisional, with the workup stated.
• 8. Grounding Gate: Any statement that cannot be traced back to your vignette is removed. No invented lab values, no assumed findings; missing data are named as missing.
• 9. Compile Validity: Statuses are normalized, confidence is capped to what the evidence supports, and the diagnostic posture (provisional vs. supported) is set by rule, not by tone.
• 10. Reconcile: In both mode, an anchored analysis (with referral context) and a blinded analysis (without it) are compared. Disagreement is surfaced, not averaged away.

What Makes This Different

• Structured Output: Diagnostic considerations include explicit reasoning explaining why each element fits or doesn't fit the presentation.
• Evidence Attribution: The system references specific findings from your vignette to support each consideration.
• Conservative Reasoning: Unknown information is explicitly marked as "needs verification" rather than assumed.
• Targeted Inquiry: The system generates specific questions to help you clarify ambiguous criteria during your patient interview.

Privacy Architecture

• Clinical vignettes exist only in memory during analysis (stateless processing).
• No patient data is stored or logged.
• All transmissions encrypted via HTTPS.
• Aliases recommended for complete de-identification.