About Diagnoxal

Structured diagnostic reasoning for mental health professionals.

The Technology

Diagnoxal uses a multi-stage Reasoning System that mirrors clinical diagnostic thinking. Unlike general AI systems that produce unstructured probability lists, Diagnoxal validates every criterion before suggesting a diagnosis.

The Reasoning Pipeline

  • 1. Extraction: Natural language processing identifies symptoms, timeline, severity, and functional impairment from your free-text vignette.
  • 2. Hypothesis Generation: The system generates multiple diagnostic possibilities simultaneously to ensure rare presentations are not overlooked.
  • 3. Structured Evaluation: Each hypothesis is tested against established diagnostic criteria with explicit evidence validation.
  • 4. Evidence Verification: Diagnoses are challenged through an adversarial review; weak matches are penalized.
  • 5. Hierarchical Exclusion: The system applies clinical logic to rule out disorders based on hierarchy (e.g., substance use or medical causes first).
  • 6. Diagnostic Parsimony: When multiple explanations fit, the system favors the simplest diagnosis that accounts for all findings.
  • 7. Comorbidity Analysis: Overlapping symptoms are analyzed to distinguish between true comorbidities versus symptom clusters.

What Makes This Different

  • Structured Output: Diagnostic considerations include explicit reasoning explaining why each element fits or doesn't fit the presentation.
  • Evidence Attribution: The system references specific findings from your vignette to support each consideration.
  • Conservative Reasoning: Unknown information is explicitly marked as "needs verification" rather than assumed.
  • Targeted Inquiry: The system generates specific questions to help you clarify ambiguous criteria during your patient interview.

Privacy Architecture

  • Clinical vignettes exist only in memory during analysis (stateless processing).
  • No patient data is stored or logged.
  • All transmissions encrypted via HTTPS.
  • Aliases recommended for complete de-identification.

How to Use Diagnoxal

1. Prepare the Clinical Vignette

Compile relevant patient information including:

  • Presenting symptoms and chief complaint
  • History of present illness
  • Mental status examination findings
  • Psychiatric history
  • Medical history and current medications
  • Relevant psychosocial factors
  • Family psychiatric history

2. De-identify Before Submission

Replace or remove:

  • Patient names → use aliases like "Patient A"
  • Dates of birth → use age only
  • Specific locations
  • Employer or school names
  • Any unique identifiers

3. Review the Analysis

You will receive:

  • Primary diagnostic considerations
  • Detailed evaluation with supporting evidence
  • Differential diagnoses with supporting/opposing factors
  • Recommendations for further evaluation
  • Safety alerts if risk factors are detected